Document Type : Review Article
Department of Biotechnology, Invertis University, Invertis Village, Bareilly-Lucknow National Highway, NH-24, Bareilly, Uttar Pradesh 243123
The appropriate drug would save lives, but it is really conceivable that perhaps the prescription that helps for others won't work in someone and will have adverse effects on other individuals. Pharmacogenomics is the new science of diverse genomic understanding and impact of drugs on the body responses. Few individual xenobiotic metabolisms disintegrate medications gradually, which can lead to serious adverse effects, while others' bodies disintegrate medications rapidly. i.e., the medication can be boon for some people whereas same medication can become curse for many people which can be life threatening. Pharmacogenomics research may detect changes for certain gene analysis of the available to the body’s natural metabolic enzymes in response to specific medications, and physicians can use this data to evaluate genetic profile and forecast if a prescription will benefit or damage before drug consumption. "The correct medication, at the correct dosage level, for the particular individual". Blood associated high pressure was previously classified as >140mmhg and >90mmhg in the United States, but current guidelines have modified the value to 130-80mmhg in order to better control and prevent hypertension. Heart rate should be between 72beats/min. Blood pressure is only deemed excessively low in practise if it causes symptoms. Hypertension has no symptoms of its own, but it destroys blood vessels over time. Such fundamental pathological conditions can also be corrected by pharmacogenomics understanding. Hypertension is also known as silent killer. For treatment of hypertension antihypertensive drugs are used like-vasodilators, diuretics and drugs that decreases cardiac output.